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available online at www sciencedirect com comprehensive psychiatry 49 2008 514 522 www elsevier com locate comppsych psychometric characteristic of the italian version of the temperament and character inventory revised ...

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                                                          Available online at www.sciencedirect.com
                                                            Comprehensive Psychiatry 49 (2008) 514–522
                                                                                                                               www.elsevier.com/locate/comppsych
             Psychometric characteristic of the Italian version of the Temperament and
                          Character Inventory—Revised, personality, psychopathology,
                                                                  and attachment styles
                                                      a                           b,                               a                                b
                       Giovanni Martinotti , Laura Mandelli ⁎, Marco Di Nicola , Alessandro Serretti ,
                                 Andrea Fossatid, Serena Borronid, C. Robert Cloningerc, Luigi Janiria
                                                aDepartment of Psychiatry, Catholic University Medical School, 00168 Rome, Italy
                                                       bInstitute of Psychiatry, University of Bologna, 40123 Bologna, Italy
                  c
                   Center for Psychobiology of Personality, Department of Psychiatry, Washington University in St, Louis, School of Medicine, St. Louis, MO, USA
                                                     dFaculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy
             Abstract
                 In this article, we described the psychometric characteristics of the revised version of the Cloninger's personality Temperament and
             Character Inventory (TCI-R), Italian translation. Two independent samples, which were composed of 355 and 385 nonclinical mother-
             language Italian subjects, respectively, completed the TCI-R. A further sample of psychiatric outpatients was compared with community
             samples. We analyzed the internal consistency of each dimension, the test-retest reliability and the factorial structure of the questionnaire.
             Furthermore, we explored the potential association between personality, psychopathologic indicators (evaluated by the Symptom Checklist-
             90), behavior dyscontrol measures, and adaptive and maladaptive interpersonal styles. As a whole, the internal consistency of the TCI-R
             scales was adequate, although some differences in Cronbach α values were observed between the 2 samples in some TCI-R subfacets. The
             factorial structure was consistent with the original hypothesis of Cloninger and test-retest showed a good stability of the scores over the time.
             Normal data for the Italian population were also calculated. Furthermore, the character dimensions of self-directedness and cooperativeness
             were related with some psychopathologic domains in our sample and negatively with impulsiveness, anger, and hostility. Novelty seeking
             wasassociated with impulsiveness, whereas harm avoidance was associated with anger and hostility. On the contrary, persistence and reward
             dependence were inversely correlated with such traits. Harm avoidance, reward dependence, self-directedness, and cooperativeness were
             strongly related with measures of attachment. Finally, significant differences were observed in both temperament and character traits between
             community subjects and psychiatric outpatients.
                 In the present study, the validity of the Italian translation of the TCI-R is therefore supported. Personality features are also confirmed as
             risk factors for specific psychopathologic domains, impulsivity, anger, and hostility. Furthermore, we found attachment styles of nonclinical
             subjects correlated with personality features.
             ©2008 Elsevier Inc. All rights reserved.
             1. Introduction                                                               persistence) and character dimensions (self-directedness
                                                                                           [SD], cooperativeness [C], self-transcendence [ST]). Tem-
                 The Temperament and Character Inventory (TCI) [1] is a                    peramental traits refer to automatic emotional responses to
             226-item self-questionnaire developed to assess the 7                         experiences that are moderately heritable and stable
             dimensions of personality defined by the biosocial model                      throughout life. In contrast, character facets refer to self-
             of personality. Cloninger and colleagues [2,3] developed this                 concepts and individual differences in goals and values and
             modelofpersonalitybasedontemperament(harmavoidance                            they are moderately influenced by insight and learning and
             [HA], novelty seeking [NS], reward dependence [RA],                           mature in progressive steps; however, some recent studies
                                                                                           showed some heritability also for character dimensions [4].
                                                                                           Temperament consists of 4 traits, so-called harm avoidance,
                 ⁎ Corresponding author. Tel.: +39 051 6584233; fax: +39 051 521030.       novelty seeking, reward dependence, and persistence. Harm
                 E-mail address: laura.mandelli@unibo.it (L. Mandelli).                    avoidance denotes the individual's inclination to behavioral
             0010-440X/$ – see front matter © 2008 Elsevier Inc. All rights reserved.
             doi:10.1016/j.comppsych.2007.11.002
                                                         G. Martinotti et al. / Comprehensive Psychiatry 49 (2008) 514–522                                       515
               inhibition in front of potentially dangerous stimuli and to                   nosis and in differentiating the individual DSM-IV person-
               anticipate negative effects; novelty seeking relates to                       ality disorder diagnoses [15].
               exploratory behaviors and activation in response to novel                         Starting from these considerations, the aim of the present
               stimuli; reward dependence concerns relational and affective                  study was to confirm and extend the psychometric properties
               skills but also others dependencies; and finally, persistence                 of Italian translation of the TCI-R also in 2 nonclinical Italian
               characterizes industrious, hard working, and stable despite                   samples. Furthermore, we aim to investigate the potential
               frustration and fatigue individuals. Character consists of 3                  association between personality and indicators of psycho-
               dimensions: SD, C, and ST. Self-directedness expresses the                    pathology, of behavior dyscontrol, adaptive, and maladap-
               individual's competence toward autonomy, reliability, and                     tive interpersonal styles. Finally, we will perform a
               maturity; cooperativeness is related to social skills, such as                comparison between scores obtained in the community
               support, collaboration, and partnership; and finally, self-                   sample with those obtained in a sample of patients affected
               transcendence denotes the aptitude toward mysticism,                          by psychiatric disorders already investigated in a previous
               religion, and idealism.                                                       study [15].
                  The TCI has been used extensively in research studies
               worldwide during the past 15 years; it provides quantitative
               measures of personality that are clinically useful in                         2. Materials and methods
               psychiatry and psychology [5] and it is a reliable instrument                 2.1. Subjects
               to assess personality disorders: lower SD and cooperative-
               ness (C) scores have been found consistently in individuals                       The investigation was performed on 2 independent
               with personality disorders [6,7]. The Italian version of the                  community samples of adult (older than 18 years)
               TCI was validated by Fossati et al [8], in both clinical and                  volunteers. The first sample was composed of 355 Italian
               nonclinical samples.                                                          mother-language subjects from the community (mostly
                  Recently, Cloninger developed a revised version of the                     members of the hospital staff), recruited at the “Agostino
               TCI(TCI-R)[9]introducing2majormodifications.First,the                         Gemelli” Hospital, Catholic University of Rome (Italy),
               original TCI was a true-false questionnaire, whereas in the                   who volunteered to take part in the study after signing a
               TCI-R, participants must respond on a 5-point Likert scale                    written informed consent form. The sample was com-
               ranging from 1 (definitively false) to 5 (definitively true) to               posed by 150 males (42.3%) and 205 females (57.7%);
               enhancetheprecisionofmeasurementforsubscales.Second,                          subjects had a mean age of 36.2 ± 14.2 years (range, 18-
               in the original TCI, Persistence was measured by only one                     86 years), and they were mainly employed (60.7%,;
               short scale, whereas in the TCI-R, this dimension has 35                      29.2% of them were students, 8.9% homemaker or
               items and 4 subscales to improve its description and                          retired, and 1.2% unemployed.
               measurement. In addition, the TCI-R adds a new subscale                           The second sample was composed of 385 Italian mother-
               for RA.                                                                       language participants living in Milan urban or suburban
                  Until recently, few data have been available about the                     areas whovolunteeredtotakepartinthestudyaftersigninga
               TCI-R. The TCI-R has been reported structurally equivalent                    written informed consent form; they were mostly members
               to the TCI and the TCI-R; a good internal consistency and                     of the San Raffaele of Hospital of Milan staff. One hundred
               factorial structure for the TCI-R have been replicated in                     sixty-three (42.3%) participants were male and 222 (57.7%)
               Belgian [10], Sweden [11], German [11], Spanish [12],                         female; participants' mean age was 32.59 ± 9.26 years. Three
               French[13],andCzech[14]populations.Recently,Fossatiet                         hundred seven participants (79.7%) were active community
               al [15] showed that the Italian translation of the TCI-R was                  workers, whereas 78 participants (20.3%) were under-
               provided with adequate reliability and validity data in a                     graduate college students. Among active community work-
               sample of 504 consecutively admitted Italian psychiatric                      ers, the most frequent professions were white-collar (n = 119.
               outpatients. Internal consistency reliabilities ranged from                   38.8%), housewife (n = 20, 6.5%), teacher (n = 17. 5.6%),
               0.79 (RA) to 0.91 (persistence) for the main TCI-R                            and blue-collar (n = 15. 4.9%). In both samples, subjects
               dimensions. In this study, 1-month test-retest reliabilities                  were not screened for psychiatric disorders or other medical
               ranged from 0.52 (NS) to 0.80 (ST), suggesting a moderate-                    conditions. To be included in the study, subjects should
               to-good stability of TCI-R scores also in treated psychiatric                 possess an education level equal to or grater than elementary
               outpatientts. Both multiple-group component and Procrustes                    school. All subjects were white.
               factor analyses suggested a close correspondence between                          The 2 samples did not differ in sex distribution (χ2 =
                                                                                                                                                                1
               the theoretical and the empirical 7-factor structure of the                   0.003, P = .096), although the second sample was slightly
               TCI-R facets also in a large sample of Italian outpatients.                   but significantly younger (t           = 4.11, P b .0001). Some
                                                                                                                               738
               Logistic regression analyses showed that the Italian transla-                 differences were observed also in other demographic
               tion of the TCI-R was efficient both in discriminating                        characteristics; in particular, the first sample included a
               subjects with any Diagnostic and Statistical Manual of                        significantly higher proportion of students than the second
               Mental Disorders, Fourth Edition (DSM-IV) personality                         sample (χ2 = 13.1, P b .0001), although the effect size of
                                                                                                          1
               diagnosis from subject with no personality disorder diag-                     this difference was at best slight (ϕ = 0.13).
            516                                    G. Martinotti et al. / Comprehensive Psychiatry 49 (2008) 514–522
            Table 1
            Mean scores and Cronbach α coefficients for TCI-R dimensions and subfacets in sample 1 and sample 2
                                                              No.                       Sample 1                                  Sample 2
                                                              of              Mean ± St dev            α               Mean ± St dev             α
                                                              item
            NS                                                35              100.5 ± 21.3              .84             98.5 ± 12.9               .78
              Exploratory excitability (NS1)                  10               30.3 ± 7.1               .28             28.7 ± 5.0                .55
              Impulsiveness (NS2)                             9                23.5 ± 6.5               .42             24.4 ± 5.3                .71
              Extravagance (NS3)                              9                27.6 ± 7.5               .07            26.25 ± 5.2                .72
              Disorderliness (NS4)                            7                19.1 ± 4.8               .24             19.3 ± 3.75               .45
            HA                                                33               92.2 ± 22.1              .88             96.4 ± 14.4              0.85
              Anticipatory worry (HA1)                        11               30.3 ± 8.1               .43             31.8 ± 5.8               0.74
              Fear of uncertainty (HA2)                       7                21.5 ± 5.2               .47             22.5 ± 3.9               0.50
              Shyness (HA3)                                   7                19.1 ± 6.2              b.01             20.4 ± 4.85              0.78
              Fatigability (HA4)                              8                21.4 ± 6.4               .23             21.7 ± 5.1               0.72
            RA                                                30              100.0 ± 19.7              .82            101.4 ± 13.0               .83
              Sentimentality (RD1)                            8                26.8 ± 5.9               .37             27.0 ± 4.2                .59
              Openness to warm communication (RD2)            10               34.8 ± 8.0               .26             34.8 ± 5.7                .75
              Attachment (RD3)                                6                19.3 ± 5.7               .17             19.5 ± 4.8                .78
              Dependence (RD4)                                6                19.2 ± 4.5               .42             20.1 ± 3.4                .36
            Persistence (P)                                   35              111.3 ± 23.3              .89            116.3 ± 14.4               .87
              Eagerness of effort (P1)                        9                30.3 ± 6.7               .76             30.6 ± 3.8                .65
              Work hardened (P2)                              8                27.3 ± 6.2               .58            27.65 ± 4.5                .62
              Ambitious (P3)                                  10               28.5 ± 6.9               .79             31.8 ± 5.9                .80
              Perfectionist (P4)                              8                25.6 ± 7.4               .36             26.3 ± 4.8                .64
            SD                                                40              136.8 ± 27.7              .82            139.1 ± 16.5               .85
              Responsibility (SD1)                            8                29.2 ± 7.7               .51             29.6 ± 4.8                .72
              Purposeful (SD2)                                6                21.6 ± 5.6              b.01             21.8 ± 3.8                .63
              Resourcefulness (SD3)                           5                18.5 ± 6.1               .47             18.2 ± 3.0                .59
              Self-acceptance (SD4)                           10               28.9 ± 8.3               .50             30.2 ± 7.0                .77
              Enlightened second nature (SD5)                 11               39.2 ± 8.7               .48             39.3 ± 5.6                .66
            C                                                 36              132.1 ± 24.0              .86            134.9 ± 13.9               .85
              Social acceptance (C1)                          8                28.9 ± 6.3               .02             29.5 ± 4.5                .76
              Empathy (C2)                                    5                18.0 ± 4.1               .13             17.9 ± 2.7                .45
              Helpfulness (C3)                                8                29.1 ± 6.8               .18             17.9 ± 3.7                .57
              Compassion (C4)                                 7                26.3 ± 5.6              b.01             26.8 ± 4.1                .62
              Pure-hearted conscience (C5)                    8                30.1 ± 6.4              b.01             31.2 ± 4.3                .60
            ST                                                26               65.6 ± 18.5              .82             69.9 ± 14.5               .84
              Self forgetful (ST1)                            10               26.1 ± 8.2               .78             27.7 ± 6.9                .74
              Transpersonal identification (ST2)              8                19.4 ± 7.7               .80             20.4 ± 5.6                .71
              Spiritual acceptance (ST3)                      8                20.4 ± 6.0               .41             21.9 ± 5.5                .64
                A third sample was compared with the community                      calculation method indicated by Cloninger [9]. To estimate
            sample. The sample has been already analyzed by Fossati                 test-retest reliability of the TCI-R and its stability over
            et al [15]. Subjects were all outpatients, affected by anxiety          time, 48 subjects in the first sample were asked to fill in
            disorders (16.7%), substance abuse/dependence disorders                 the questionnaire twice, after a minimum of 6 months till a
            (20.8%), eating disorders (11.1%), mood disorders (28,
            5.6%), and other DSM-IVAxis I diagnosis (sleep disorders,
            sexual disorders, somatoform disorders, etc) (3.6%). A large
            part of the sample received a diagnosis of personality                  Table 2
            disorder (65.9%). For further details, the reader can refer to          Cronbach α coefficients for TCI-R dimensions in males, females and
            the article of Fossati et al [15].                                      stratified for three cohort of age
                                                                                        Cronbach   Cronbach    Cronbach α   Cronbach α   Cronbach α
                                                                                        α (males)  α (females) (age ≤24 y)  (age 25-49 y) (age ≥50 y)
            2.2. Measures                                                           NS 0.81        0.86        0.91         0.75         0.83
                All subjects filled in the TCI-R; no serious acceptability          HA 0.87        0.88        0.92         0.84         0.84
            or comprehension difficulties appeared in the completion.               RD 0.79        0.83        0.93         0.71         0.72
                                                                                    P   0.88       0.90        0.91         0.87         0.90
            The Italian version of the TCI-R was translated by M                    SD 0.84        0.83        0.91         0.82         0.77
            Battaglia, a professional English translator who evaluated              C   0.86       0.90        0.95         0.81         0.87
            its adequacy to its respective English version through a                ST 0.80        0.86        0.91         0.78         0.78
            back-version. TCI-R was analyzed in accordance with the                 P indicates persistence.
                                                         G. Martinotti et al. / Comprehensive Psychiatry 49 (2008) 514–522                                       517
               Table 3                                                                       analysis of covariance controlling for sex and age and
               Test-retest reliability: ICC (n = 48)                                         post hoc by the contrast analysis.
                               Time 1                    Time 2                   ICC            ABonferroni correction was systematically applied when
               NS               99.5 ± 16.2              100.5 ± 15.1             0.81       analyzing SCL-90, BIS-11, AQ, and ASQ scores. Overall, α
               HA               93.0 ± 14.3               91.8 ± 14.4             0.88       levels ranged from 0.001 to 0.0009. With these parameters,
               RD               74.2 ± 16.7               72.0 ± 15.1             0.87       weobtained a sufficient power of 0.80 to detect small effect
               P               114.1 ± 17.4              114.5 ± 17.5             0.83       sizes (r = 0.235) for correlations between TCI-R and SCL
               SD              143.1 ± 19.3              146.5 ± 20.6             0.80       scores; between TCI-R, BIS-11, and AQ scores (r = 0.21);
               C               139.5 ± 12.8              140.0 ± 13.7             0.68
               ST               69.3 ± 16.1               68.7 ± 17.2             0.76       and between TCI-R and ASQ scores (r = 0.20).
                                                                                             3. Results
               maximum of 8 months from the first administration. In the
               first  sample, 235 subjects were also evaluated for                               Meanscores of main dimensions and facets of the TCI-R
               psychopathologic and general symptoms by the Symptom                          for samples 1 and 2 are shown in Table 1.
               Checklist (SCL-90) [16]. Ninety-three subjects were also                          Because this new version of the TCI gives the choice to
               investigated for psychiatric family history by the Family                     answer “neither true nor false,” or about equally “true or
               Abbreviated Interview (FAI) [17]. Of 93, 62 subjects                          false” (response 3), it is of interest to know if some items
               (66.7%) were positive for familiar psychiatric disorders; the                 frequently received this response. The item with the highest
               most frequent familiar disorders were depression (41.9%)                      rates of this response in our samples was the 161 (47.1%, “I
               and eating disorders (18.3%). Subjects with positive and                      think I will have very good luck in the future” from HA1),
               negative family history for psychiatric disorders were not                    according to reference [13]. Other items that frequently
               different for sex, gender, and social status. In the second                   scored 3 were the 81 (38.1% from HA4), 117 (40,6%, from
               sample, to extend the construct validity data of the TCI-R,                   P3), 55 (42.5%, from P4), and 76 (39.8%, from P4).
               all subjects were administered the Italian versions of the                    3.1. Internal consistency
               Barratt Impulsiveness Scale-11 (BIS-11 [18]), Aggression
               Questionnaire (AQ [19]), and Attachment Style Question-                           The internal consistency of the main dimensions and
               naire (ASQ [20]). The Italian versions of the BIS-11, AQ                      subfacets has been explored by the mean of the Cronbach α
               and ASQ were provided with adequate reliability and                           coefficient on both samples and presented in Table 1. All
               validity data [8,21,22].                                                      TCI-R main dimensions showed adequate internal consis-
                  Data were analyzed by simple pairwise case deletion. In                    tency coefficients (≥70). At the facet level, almost all TCI-R
               fact, in both samples, no other variable was missing in more                  facets showed adequate internal consistencies in sample 2,
               than 5% of cases, except for the educational level in sample                  whereas low reliability values were observed in sample 1.
               1. Nevertheless, by the missing value analysis, education
               was missing completely at random and it did not affect any
               other variable in the sample.                                                 Table 4
               2.3. Statistical analysis                                                     Principal-component analysis of temperament subscales (Varimax
                                                                                             transformation including factors with eigenvalue of 1 or more)
                  The internal consistency of the scores and subscores of                                               Factor 1    Factor 2    Factor 3     Factor 4
               TCI-R was calculated through the Cronbach α coefficient.                                                 P           HA          NS          RD
               To explore the effect of sex and age on internal                              NS1                         0.38       −0.05         0.64        0.40
               consistency, we calculated the coefficient separately in                      NS2                         0.09        0.12         0.84        0.08
               men and women and in 3 different cohorts of age (divided                      NS3                         0.11        0.12         0.72        0.38
               according to lower and upper quartiles of the distribution                    NS4                         0.18        0.17         0.78        0.16
               of age). Exploratory principal-components analyses with                       HA1                         0.12        0.87         0.12      −0.02
               Varimax transformation were performed to analyze the                          HA2                         0.19        0.84         0.06        0.18
               factorial structure of the questionnaire; and to explore test-                HA3                         0.03        0.85       −0.01       −0.08
                                                                                             HA4                        −0.10        0.79         0.19        0.10
               retest reliability, intraclass correlation coefficients (ICCs)                RD1                         0.36        0.49         0.24        0.49
               were calculated for each TCI dimension. Raw TCI-R                             RD2                         0.41        0.02         0.30        0.77
               scores were then converted to T scores (distribution's                        RD3                         0.15        0.02         0.19        0.88
               mean, 50; St dev, 10) to provide normal data. Association                     RD4                         0.24        0.49         0.06        0.53
               of TCI-R scores with age, sex, SCL-90, BIS-11, AQ, and                        PS1                         0.82        0.13         0.17        0.23
               ASQ scores and family history for psychiatric disorders                       PS2                         0.85        0.08         0.15        0.21
                                                                                             PS3                         0.81        0.00         0.26        0.21
               (FAI) were explored by the correlation analysis and the                       PS4                         0.83        0.11       −0.03         0.07
               Student t test. The comparison between TCI-R scores in                        Explained variance (%)     21.07       21.23        16.36       15.12
               community and PD subjects was performed by the                                Loadings with absolute values of 0.50 or more are shown in boldface type.
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...Available online at www sciencedirect com comprehensive psychiatry elsevier locate comppsych psychometric characteristic of the italian version temperament and character inventory revised personality psychopathology attachment styles a b giovanni martinotti laura mandelli marco di nicola alessandro serretti andrea fossatid serena borronid c robert cloningerc luigi janiria adepartment catholic university medical school rome italy binstitute bologna center for psychobiology department washington in st louis medicine mo usa dfaculty psychology vita salute san raffaele milan abstract this article we described characteristics cloninger s tci r translation two independent samples which were composed nonclinical mother language subjects respectively completed further sample psychiatric outpatients was compared with community analyzed internal consistency each dimension test retest reliability factorial structure questionnaire furthermore explored potential association between psychopathologic...

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