Monash-
                                                                                                   Industry 
                                                                                                   Palm Oil 
                                                                                                   Platform
                Nutrition and Immunity:: 
         Evidence Using Tocotrienols
                                       Ammu K Radhakrishnan
                                           Professor (Immunology)
                            Jeffrey Cheah School of Medicine and Health Sciences
                                  Monash Industry Palm Oil (MIPO) Platform
                                         Monash University Malaysia
                                   ammu.radhakrishnan@monash.edu
                                                                                 Monash-
                                                                                 Industry 
                                                                                 Palm Oil 
                    Presentation Outline                                         Platform
       • Overview of the immune system
       • Tocotrienols
       • Research evidence: Effects of 
          tocotrienols on immune system
       • Concluding remarks
       4 June, 2020             Ammu K Radhakrishnan, Monash University Malaysia   2
                                                                                 Monash-
                                                                                 Industry 
                                                                                 Palm Oil 
                                                                                 Platform
                                                 Identify & destroy abnormal cells 
     Immunity against invading pathogens         Cancer cells, damaged cells, 
    Bacteria, virus, parasites                   mutated cells
    1. Prevent infections
    2. Fight pathogens                     Immune 
    3.  Acquired immunity 
       against pathogens                   System
                                                         Undesirable effects
            Repair & Healing                             Immunodeficiency
    Remove old cells (e.g. old RBC)                      Allergy
    Remove dead cells (e.g. tissue                       Autoimmune diseases
    debris)                                              Rejection of transplants
     4 June, 2020               Ammu K Radhakrishnan, Monash University Malaysia   3
                                                                                 Monash-
                                                                                 Industry 
                                                                                 Palm Oil 
                                                                                 Platform
                             Immune Responses
                          Innate                   Adaptive
                                Systemic
                                Mucosal
     4 June, 2020               Ammu K Radhakrishnan, Monash University Malaysia   4