PROGNOSTIC SIGNIFICANCE OF HIGHLY 
               SENSITIVE C-REACTIVE PROTEIN IN ACUTE 
                      ISCHEMIC STROKE PATIENTS  
             
                          DISSERTATION SUBMITTED FOR 
                                      
                        DOCTOR OF MEDICINE 
                     BRANCH - I (GENERAL MEDICINE) 
                                APRIL 2013 
                                      
                                      
                                      
                                      
                                      
                                      
                                      
                            THE TAMILNADU  
                    DR.M.G.R.MEDICAL UNIVERSITY  
                                CHENNAI  
                                      
                                      
                                      
                                      BONAFIDE CERTIFICATE 
                          This is to certify that the dissertation entitled “PROGNOSTIC 
                  SIGNIFICANCE  OF  HIGHLY  SENSITVE  C-REACTIVE 
                  PROTEIN  IN  ACUTE  ISCHEMIC  STROKE  PATIENTS” 
                  submitted  by  Dr.J.RAJ  KUMAR  to  the  Tamil  Nadu  Dr. 
                  M.G.R.Medical University, Chennai in partial    fulfillment of the 
                  requirement  for  the  award  of  M.D  Degree  Branch  I  (General 
                  Medicine) is a bonafide research work was carried out by him under 
                  my direct supervision & guidance. 
                   
                   
                   
                  Prof.Dr.M.NATARAJAN M.D.,                    Prof.Dr.Moses K Daniel M.D., 
                  Unit Chief,                                  Head of the Department, 
                  Department of Medicine,                      Department of Medicine, 
                  Madurai Medical College,                        Madurai Medical College, 
                  Madurai.                                     Madurai. 
                   
                                                          
                                                          
                                                          
                                                          
                                                                                        
                                                                    DECLARATION 
                                      I, Dr.J.RAJ KUMAR declare that, I carried out this work on, 
                           “PROGNOSTIC  SIGNIFICANCE  OF  HIGHLY  SENSITIVE  C-
                           REACTIVE  PROTEIN  IN  ACUTE  ISCHEMIC  STROKE 
                           PATIENTS” at the Department of Medicine, Govt. Rajaji Hospital 
                           during the period of March 2012 to October 2012.  I also declare that 
                           this bonafide work or a part of this work was not submitted by me or 
                           any others for any award, degree, diploma to any other University, 
                           Board either in India or abroad. 
                                      This  is  submitted  to  The  Tamilnadu  Dr.M.G.R.Medical 
                           University, Chennai in partial fulfillment of the rules and regulations 
                           for the M.D degree  examination in General Medicine. 
                            
                           Place  : Madurai                                                        Dr. J. RAJ KUMAR 
                           Date   : 
                            
                   ACKNOWLEDGEMENT 
          At the outset, I wish to thank our Dean Dr.N.Mohan M.S.,F.I.C.S, for 
      permitting  me  to  use  the  facilities  of  Madurai  Medical  College  and 
      Government Rajaji Hospital to conduct this study. 
          My beloved unit  chief  Prof.  Dr.M.Natarajan  M.D.,  and  Head  of  the 
      Department of Medicine, Prof. Dr.Moses.K.Daniel M.D., has always guided 
      me, by example and valuable words of advice and has given me his moral 
      support and encouragement through the conduct of the study and also during 
      my postgraduate course. I will be ever grateful to him. 
          I am extremely grateful to the professor and Head of the Department of 
      Neurology,  Prof.Dr.  Muthuveeran  M.D.D.M.,  without  whose  constant 
      support, guidance, cooperation and encouragement this dissertation would not 
      have been possible. 
          I  offer  my  heartfelt  thanks  to  my  two  unit  Assistant  Professors  
      Dr.K.Muralidaran  M.D.,  Dr.Ganesh  Babu  M.D.,  for  their  constant 
      encouragement, timely help and critical suggestions throughout the study and 
      also for making my stay in the unit both informative and pleasurable.